Alkyne Phosphoramidite, 5'-terminal, for the synthesis of oligonucleotides (ab235034)
Key features and details
- Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry.
- CAS Number: 1417539-32-2
- Purity: > 95%
Acetonitrile (good solubility)
Dichloromethane (good solubility)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Alkyne Phosphoramidite, 5'-terminal, for the synthesis of oligonucleotides -
Description
Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry. -
Biological description
Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry. Easier to handle and dispense, and more stable compared to 5’-hexynyl phosphoramidite, 5'-butynyl-CEP, and other 5'-terminal alkyne phosphoramidites. Use acetonitrile as diluent. A 5 minute coupling time is recommended using standard nucleobase conditions. 5'-deprotection not needed due to lack of 5'-terminal DMT group. Oligonucleotides can be deblocked under standard conditions and purified by PAGE or HPLC ion-exhange chromatography.
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Purity
> 95% -
CAS Number
1417539-32-2 -
Chemical structure
Properties
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Chemical name
trans-4-(5-Hexynoylamino)cyclohexyloxy-N,N-diisopropylamino-2-cyanoethyloxyphosphine
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Molecular weight
409.50 -
Molecular formula
C21H36N3O3P -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Acetonitrile (good solubility)
Dichloromethane (good solubility)
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Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
