Agomelatine, MT1/MT2 agonist and 5-HT2C antagonist (ab142476)
Key features and details
- Potent MT1/MT2 agonist and 5-HT2C antagonist
- CAS Number: 138112-76-2
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Agomelatine, MT1/MT2 agonist and 5-HT2C antagonist -
Description
Potent MT1/MT2 agonist and 5-HT2C antagonist -
Biological description
Potent MT1/MT2 agonist (Ki values are 0.1 and 0.12 nM, respectively). 5-HT2C antagonist (IC50 = 270 nM). Shows antidepressant effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
138112-76-2 -
Chemical structure
Properties
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Chemical name
N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide -
Molecular weight
243.30 -
Molecular formula
C15H17NO2 -
PubChem identifier
82148 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC -
Source
Synthetic
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Research areas