ACTH (4-10) (human), melanocortin receptor agonist fragment (ab142255)
Key features and details
- Potent melanocortin receptor agonist and endogenous adrenocorticotropic hormone (ACTH) fragment
- CAS Number: 4037-01-8
- Purity: > 95%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ACTH (4-10) (human), melanocortin receptor agonist fragment -
Description
Potent melanocortin receptor agonist and endogenous adrenocorticotropic hormone (ACTH) fragment -
Biological description
Potent melanocortin (MC) receptor agonist and endogenous adrenocorticotropic hormone (ACTH) fragment (EC50 values are 23 and 330 nM for MC3 and MC4 receptors respectively). Has multiple biological activities. Analgesic, neuroprotective and prevents ischemia-induced cardiac injury. Active in vivo. -
Purity
> 95% -
CAS Number
4037-01-8 -
Chemical structure
Properties
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Molecular weight
962.10 -
Molecular formula
C44H59N13O10S -
Sequence
MEHFRWG -
PubChem identifier
123787 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)N -
Source
Synthetic
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Research areas
