2,3-Butanedione 2-monoxime (BDM), Non-selective myosin ATPase inhibitor (ab120616)
Key features and details
- Non-selective myosin ATPase inhibitor
- CAS Number: 57-71-6
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2,3-Butanedione 2-monoxime (BDM), Non-selective myosin ATPase inhibitor -
Description
Non-selective myosin ATPase inhibitor -
Alternative names
- BDM
- Biacetyl monoxime
- Diacetyl monoxime
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Biological description
Non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Potent Kv2.1 (DRK1) and L-Type Ca2+ channel inhibitor (Ki and IC50 values are 10.7 nM and 5.8 mM, respectively). Blood-brain barrier permeable. Inhibits muscle contraction.
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CAS Number
57-71-6 -
Chemical structure
Properties
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Chemical name
2,3-Butanedione monoxime -
Molecular weight
101.10 -
Molecular formula
C4H7NO2 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas