Alendronate monosodium trihydrate, bone resorption inhibitor (ab141897)
Key features and details
- Potent bone resorption inhibitor
- CAS Number: 121268-17-5
- Soluble in water to 100 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Alendronate monosodium trihydrate, bone resorption inhibitor -
Description
Potent bone resorption inhibitor -
Biological description
Potent bone resorption inhibitor. Inhibits farnesyl synthase (IC50 = 460 nM) and the isoprenoid biosynthesis pathway. Able to increase TGF-β1 levels. Active in vivo and in vitro.
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CAS Number
121268-17-5 -
Chemical structure
Properties
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Chemical name
P,P'-(4-Amino-1-hydroxybutylidene)bisphosphonic acid sodium salt trihydrate -
Molecular weight
325.08 -
Molecular formula
C4H12NNaO7P2.3H2O -
PubChem identifier
23681107 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+] -
Source
Synthetic
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Research areas
