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Cardiovascular Atherosclerosis Thrombosis Platelets

AA 2414 (Seratrodast), TXA2 antagonist (ab142947)

Key features and details

  • Potent and selective TXA2 antagonist
  • CAS Number: 112665-43-7
  • Purity: > 98%
  • Soluble in DMSO to 25 mM and in ethanol to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    AA 2414 (Seratrodast), TXA2 antagonist
  • Description

    Potent and selective TXA2 antagonist
  • Biological description

    Potent and selective TXA2 antagonist (IC50 = 7-350 nM). Shows bronchiodilatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    112665-43-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid
  • Molecular weight

    354.44
  • Molecular formula

    C22H26O4
  • PubChem identifier

    2449
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM and in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=C(C(=O)C(=C(C1=O)C)C(CCCCCC(=O)O)C2=CC=CC=C2)C
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Blood
    • Platelets
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Platelets
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Prostanoid
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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