A 943931 dihydrochloride, H4 receptor antagonist (ab142809)
Key features and details
- Potent and selective H4 receptor antagonist
- CAS Number: 1227675-50-4
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
A 943931 dihydrochloride, H4 receptor antagonist -
Description
Potent and selective H4 receptor antagonist -
Biological description
Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
1227675-50-4 -
Chemical structure
Properties
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Chemical name
4-[(3R)-3-Amino-1-pyrrolidinyl]-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine dihydrochloride -
Molecular weight
368.31 -
Molecular formula
C17H21N5.2HCl -
PubChem identifier
56972240 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.Nc1nc3c4ccccc4CCCc3c(n1)N2CC[C@@H](N)C2 -
Source
Synthetic
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Research areas