8-Br-cAMP (8-Bromo-cAMP), PKA activator (ab141448)
Key features and details
- cAMP analog. PKA activator.
- CAS Number: 76939-46-3
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
8-Br-cAMP (8-Bromo-cAMP), PKA activator -
Description
cAMP analog. PKA activator. -
Alternative names
- 8-Bromo-cAMP
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Biological description
Cell-permeable cAMP analog. Activates PKA. Inhibits cell growth, decreases proliferation and increases differentiation. Additionally induces apoptosis. Also improves reprogramming efficiency of fibroblast cells.
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Purity
> 99% -
CAS Number
76939-46-3 -
Chemical structure
Properties
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Chemical name
8-Bromoadenosine-3′,5′-cyclic monophosphate sodium salt -
Molecular weight
430.09 -
Molecular formula
C10H10BrN5NaO6P -
PubChem identifier
23712387 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] -
Source
Synthetic
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Research areas
