6-Thioguanine, Antimetabolite (ab142729)
Key features and details
- Antimetabolite. Guanine analog.
- CAS Number: 154-42-7
- Purity: > 90%
- Soluble in DMSO to 100mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
6-Thioguanine, Antimetabolite -
Description
Antimetabolite. Guanine analog. -
Biological description
Antimetabolite. Guanine analogue. Incorporates into mitochondrial DNA and induces DNA double-strand breaks. Antitumor, immunosuppressive and anti-inflammatory effects in vivo. Metabolite of Azathioprine (ab143064). Orally active. -
Purity
> 90% -
CAS Number
154-42-7 -
Chemical structure
Properties
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Chemical name
2-Amino-3,7-dihydropurine-6-thione -
Molecular weight
167.19 -
Molecular formula
C5H5N5S -
PubChem identifier
2723601 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=NC2=C(N1)C(=S)N=C(N2)N -
Source
Synthetic
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Research areas
