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Cyproterone acetate, Androgen receptor antagonist (ab142416)

Key features and details

  • Androgen receptor antagonist
  • CAS Number: 427-51-0
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Cyproterone acetate, Androgen receptor antagonist
  • Description

    Androgen receptor antagonist
  • Biological description

    Androgen receptor antagonist (IC50 = 7.1 nM). Competes with dihydrotestosterone at androgen receptor sites. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    427-51-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Chloro-1β,2β-dihydro-17-hydroxy-3′H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate
  • Molecular weight

    416.94
  • Molecular formula

    C24H29ClO4
  • PubChem identifier

    9880
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)OC(=O)C
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Cardiovascular
    • Hypoxia
    • Hypoxia-Regulated
    • Cardiovascular
    • Angiogenesis
    • Growth Factors
    • FGF
    • FGF Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Opioid Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • More GPCR
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Coagulation
    • Regulatory
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Cell Biology
    • Apoptosis
    • Phagocytosis
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Progesterone
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Corticoid
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Testosterone
    • Neuroscience
    • Sensory System
    • Somatosensory system
    • Nociception
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Neuroscience
    • Neurology process
    • Neurogenesis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Corticoid
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Progesterone
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Testosterone
    • Epigenetics and Nuclear Signaling
    • Cardiovascular/Immune
    • Hypoxia
    • Hypoxia regulated
    • Cell Biology
    • Other Antibodies
    • Drugs and Chemicals
    • Cancer
    • Invasion/microenvironment
    • Hypoxia
    • Hypoxia-related proteins
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    • Nuclear hormone receptors
    • Progesterone
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Other
    • Cancer
    • Tumor biomarkers
    • Receptors
    • Cardiovascular
    • Atherosclerosis
    • Ischemia / Reperfusion
    • Cardiovascular
    • Atherosclerosis
    • Vascular Inflammation
    • Inflammatory mediators
    • Cardiovascular
    • Heart
    • Cardiac arrhythmias
    • Neuroscience
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    • Metabolism processes
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    • Phagocytosis
    • Cancer
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    • Apoptosis
    • Receptors
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    • Cancer
    • Cell Death
    • Apoptosis
    • Metabolism

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