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Biochemicals Product Range New

3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase (ab146627)

Key features and details

  • Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor
  • CAS Number: 102052-95-9
  • Purity: > 98%
  • Supplied in DMSO (10 mM)
  • Form / State: Liquid
  • Source: Synthetic

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Overview

  • Product name

    3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase
  • Description

    Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor
  • Biological description

    Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor. Induces cancer cell selective apoptosis. Shows antitumor effects in vivo.

    Also available as a solid (ab142215).
  • Purity

    > 98%
  • CAS Number

    102052-95-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1S,2R,5R)-5-(4-Aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
  • Molecular weight

    262.26
  • Molecular formula

    C12H14N4O3
  • PubChem identifier

    73087
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CN=C(C2=C1N(C=N2)[C@@H]3C=C([C@H]([C@H]3O)O)CO)N
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Hydrolase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Transferase
    • Histone Methyltransferase (HMT)
    • Other

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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