3-Bromo-7-nitroindazole, nNOS and iNOS inhibitor (ab144716)
Key features and details
- nNOS and iNOS inhibitor
- CAS Number: 74209-34-0
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
3-Bromo-7-nitroindazole, nNOS and iNOS inhibitor -
Description
nNOS and iNOS inhibitor -
Biological description
Neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) inhibitor (IC50 = 0.86 μM, 0.17 μM and 0.29 μM for bovine endothelial, rat cerebellar and rat lung NOS enzyme activity respectively). Active in vivo. -
CAS Number
74209-34-0 -
Chemical structure
Properties
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Chemical name
3-Bromo-7-nitro-1H-indazole -
Molecular weight
242.03 -
Molecular formula
C7H4BrN3O2 -
PubChem identifier
1649 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br -
Source
Synthetic
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Research areas
