2', 7'-Dichlorofluorescin diacetate (ab273640)
Key features and details
- Cell-permeable ROS probe
- CAS Number: 4091-99-0
Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
2', 7'-Dichlorofluorescin diacetate -
Description
Cell-permeable ROS probe -
Alternative names
- H2DCFDA
-
Biological description
Cell-permeable ROS probe. Reduced derivative of 2',7'-dichlorofluorescein. Can detect reactive oxygen species in live cells. Detects peroxidase activity (oxidative metabolism, intracellular regulation of ROS or oxidative burst). Upon enzyme activity, the highly fluorescent dye 2',7'-dichlorofluorescein is produced (Ex/Em = 495/529 nm).
-
Purity
98% -
CAS Number
4091-99-0 -
Chemical structure
Properties
-
Chemical name
2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid
-
Molecular weight
487.30 -
Molecular formula
C24H16Cl2O7 -
PubChem identifier
77718 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM
-
Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC(=O)OC1=C(C=C2C(C3=CC(=C(C=C3OC2=C1)OC(=O)C)Cl)C4=CC=CC=C4C(=O)O)Cl -
Source
Synthetic
Images
-
2', 7'-Dichlorofluorescin diacetate (ab273640)
