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Biochemicals

15-Acetyl-deoxynivalenol (15-ADON), Type B trichothecene mycotoxin (ab143561)

Key features and details

  • Type B trichothecene mycotoxin
  • CAS Number: 88337-96-6
  • Purity: > 98%
  • Form / State: Solid
  • Source: Fusarium graminearum

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Overview

  • Product name

    15-Acetyl-deoxynivalenol (15-ADON), Type B trichothecene mycotoxin
  • Description

    Type B trichothecene mycotoxin
  • Biological description

    Type B trichothecene mycotoxin. Deoxynivalenol (ab143487) and 3-Acetyldeoxynivalenol (ab143561) analog. Protein synthesis inhibitor. Binds to rRNA. Induces TNF-α, IL-1β, IL-6, CXCL-2, CCL-2 and CCL-7 mRNA expression. Shows emetic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    88337-96-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    15-Acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one
  • Molecular weight

    338.35
  • Molecular formula

    C17H22O7
  • PubChem identifier

    10382483
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)COC(=O)C
  • Source

    Fusarium graminearum

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Chemical Type
    • Toxin
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • Protein synthesis

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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