10058-F4, c-Myc-Max dimerization inhibitor (ab145065)
Key features and details
- Cell-permeable c-Myc-Max dimerization inhibitor
- CAS Number: 403811-55-2
- Purity: > 99%
- Soluble in ethanol to 25 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
10058-F4, c-Myc-Max dimerization inhibitor -
Description
Cell-permeable c-Myc-Max dimerization inhibitor -
Biological description
Cell-permeable c-Myc-Max dimerization inhibitor. Downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27. Inhibits proliferation. Induces apoptosis and cell cycle arrest in G0/G1 phase. Shows antitumor effects in vivo.
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Purity
> 99% -
CAS Number
403811-55-2 -
Chemical structure
Properties
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Chemical name
5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone -
Molecular weight
249.35 -
Molecular formula
C12H11NOS2 -
PubChem identifier
1271002 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 25 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2 -
Source
Synthetic
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Research areas