Z-LLY-FMK, Calpain inhibitor (ab141385)
Key features and details
- Irreversible, cell-permeable calpain inhibitor
- CAS Number: 133410-84-1
- Purity: > 95%
- Supplied in DMSO (10 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Z-LLY-FMK, Calpain inhibitor -
Description
Irreversible, cell-permeable calpain inhibitor -
Biological description
Irreversible, cell-permeable calpain inhibitor. Reduces Gal-9-induced apoptosis in vitro. Suppresses hepatocyte apoptosis after bile duct ligation in rat. Active in vivo and in vitro. -
Purity
> 95% -
CAS Number
133410-84-1 -
Chemical structure
Properties
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Molecular weight
557.70 -
Molecular formula
C30H40FN3O6 -
Sequence
LLY (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK) -
PubChem identifier
16760337 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Supplied in DMSO (10 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)CF)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2 -
Source
Synthetic
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Research areas