YIL781 hydrochloride, Ghrelin receptor antagonist (ab141106)
Key features and details
- Ghrelin receptor antagonist
- CAS Number: 875258-85-8
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
YIL781 hydrochloride, Ghrelin receptor antagonist -
Description
Ghrelin receptor antagonist -
Biological description
Ghrelin receptor (GHS-R1a) antagonist (Ki = 17 nM). Competitive antagonist activity in vitro (pKB = 7.54). Displays no affinity for the motilin receptor (Ki = 6 μM).
-
Purity
> 99% -
CAS Number
875258-85-8 -
Chemical structure
Properties
-
Chemical name
6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone hydrochloride -
Molecular weight
445.96 -
Molecular formula
C24H28FN3O2.HCl -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Cl.CC(C)N4CCC[C@H](CN3C(C)=Nc2ccc(Oc1ccc(F)cc1)cc2C3=O)C4 -
Source
Synthetic
-
Research areas