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Yangonin, NF-kappabeta inhibitor (ab142563)

Key features and details

  • Potent NF-κβ inhibitor. Selective CB1 agonist. Antioxidant.
  • CAS Number: 500-62-9
  • Purity: > 98%
  • Soluble in ethanol (with heating)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Yangonin, NF-kappabeta inhibitor
  • Description

    Potent NF-κβ inhibitor. Selective CB1 agonist. Antioxidant.
  • Biological description

    Potent NF-κβ inhibitor. Selective CB1 agonist. (Ki values are 0.7 and 10 μM for CB1 and CB2 respectively). Shows potent antioxidant effects. Active in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    500-62-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]pyran-2-one
  • Molecular weight

    258.27
  • Molecular formula

    C15H14O4
  • PubChem identifier

    5281575
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol (with heating)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC=C(C=C1)C=CC2=CC(=CC(=O)O2)OC
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Cannabinoid Receptor
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors
    • Cell Biology
    • Other Antibodies
    • Oxidative Stress
    • Cancer
    • Signal transduction
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    • Nuclear hormone receptors
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    • Metabolic signaling pathways
    • Nucleotide metabolism
    • Molecular processes
    • Mitochondrial transcription
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Oxidative stress

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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