WS 12, TRPM8 agonist (ab145195)
Key features and details
- Potent, selective TRPM8 agonist
- CAS Number: 68489-09-8
- Purity: > 98%
- Soluble in ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
WS 12, TRPM8 agonist -
Description
Potent, selective TRPM8 agonist -
Biological description
Potent, selective TRPM8 agonist (EC50 = 193 nM). Increases intracellular Ca2+ concentration. Reduces epidermal proliferation associated with barrier disruption. Shows cooling effects in vivo. -
Purity
> 98% -
CAS Number
68489-09-8 -
Chemical structure
Properties
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Chemical name
(1R,2S,5R)-N-(4-Methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide -
Molecular weight
289.42 -
Molecular formula
C18H27NO2 -
PubChem identifier
11266244 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1CC[C@H]([C@@H](C1)C(=O)NC2=CC=C(C=C2)OC)C(C)C -
Source
Synthetic
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Research areas
