Wortmannin, PI3-kinase inhibitor (ab120148)
Key features and details
- PI3-kinase inhibitor
- CAS Number: 19545-26-7
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Penicillium funiculosum
Overview
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Product name
Wortmannin, PI3-kinase inhibitor -
Description
PI3-kinase inhibitor -
Biological description
Potent, selective and cell-permeable inhibitor of phosphatidylinositol-3-kinase (PI3-kinase) (IC50 ~ 3 nM)
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Purity
> 98% -
CAS Number
19545-26-7 -
Chemical structure
Properties
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Chemical name
(1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,h]-2-h]-2-benzopyran-3,6,9-trione -
Molecular weight
428.44 -
Molecular formula
C23H24O8 -
PubChem identifier
312145 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)O[C@@H]4C[C@]5(C)C(=O)CC[C@H]5C=3C(=O)c2occ1C(=O)O[C@H](COC)[C@@](C)(c12)C=34 -
Source
Penicillium funiculosum
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Research areas
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- PI3K/Akt signaling
- PI3-kinase
- Inhibitors
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- PI3K/Akt signaling
- PI3-kinase
- Inhibitors
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- PI3K/Akt signaling
- PI3-kinase
- Inhibitors
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- PI3K/Akt signaling
- PI3-kinase
- Inhibitors