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Signal Transduction Signaling Pathway Lipid Signaling Lipid Kinases

Wortmannin, PI3-kinase inhibitor (ab120148)

Price and availability

184 272 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • PI3-kinase inhibitor
  • CAS Number: 19545-26-7
  • Purity: > 98%
  • Soluble in DMSO to 50 mM and in ethanol to 5 mM
  • Form / State: Solid
  • Source: Penicillium funiculosum

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Overview

  • Product name

    Wortmannin, PI3-kinase inhibitor
  • Description

    PI3-kinase inhibitor
  • Biological description

    Potent, selective and cell-permeable inhibitor of phosphatidylinositol-3-kinase (PI3-kinase) (IC50 ~ 3 nM)

  • Purity

    > 98%
  • CAS Number

    19545-26-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,h]-2-h]-2-benzopyran-3,6,9-trione
  • Molecular weight

    428.44
  • Molecular formula

    C23H24O8
  • PubChem identifier

    312145
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM and in ethanol to 5 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)O[C@@H]4C[C@]5(C)C(=O)CC[C@H]5C=3C(=O)c2occ1C(=O)O[C@H](COC)[C@@](C)(c12)C=34
  • Source

    Penicillium funiculosum

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