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Immunology Immune Interventions Transplantation

WAY 262611, Wnt pathway activator (ab145229)

Key features and details

  • Wnt pathway activator
  • CAS Number:
  • Purity: > 97%
  • Soluble in ethanol to 75 mM and in DMSO to 75 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    WAY 262611, Wnt pathway activator
  • Description

    Wnt pathway activator
  • Biological description

    Wnt pathway activator. Selectively inhibits Dkk1 with no GSK-3β inhibition. TCF-Luciferase agonist (EC50 = 0.63 µM). Increases bone formation rate in vivo. Orally active.
  • Purity

    > 97%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [1-(4-Naphthalen-2-ylpyrimidin-2-yl)piperidin-4-yl]methanamine
  • Molecular weight

    318.40
  • Molecular formula

    C20H22N4
  • PubChem identifier

    25199517
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 75 mM and in DMSO to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Immune Interventions
    • Transplantation
    • Cardiovascular
    • Blood
    • Other
    • Stem Cells
    • Signaling Pathways
    • Wnt
    • Secreted
    • Developmental Biology
    • Embryogenesis
    • Axis formation and symmetry
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Wnt signaling
    • Activators

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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