Vistusertib (AZD2014) (ab273620)
Key features and details
- Potent and selective mTOR inhibitor
- CAS Number: 1009298-59-2
- Purity: > 98%
Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Vistusertib (AZD2014) -
Description
Potent and selective mTOR inhibitor -
Biological description
Novel potent and selective mammalian rapamycin (mTOR) inhibitor (IC50 = 2.8 nM). Highly selective against multiple PI3K isoforms. Also targets P-Akt (IC50 = 80 nM) and pS6 (IC50 = 200 nM). An oral inhibitor with potential anti-neoplastic activity.
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Purity
> 98% -
General notes
For obtaining a higher solubility, please warm the tube at 37°C and shake in the ultrasonic bath for a while.
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CAS Number
1009298-59-2 -
Chemical structure
Properties
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Chemical name
3-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-N-methylbenzamide
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Molecular weight
462.54 -
Molecular formula
C25H30N6O3 -
PubChem identifier
25262792 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=CC=C4)C(=O)NC)N5CCOC[C@@H]5C -
Source
Synthetic
Images
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Chemical Structure - Vistusertib (AZD2014) (ab273620)
Chemical structure of Vistusertib (AZD2014), 1009298-59-2