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Immunology Immunoglobulins Heavy Chain IgG

violetFluor™ 450 Mouse IgG2b, monoclonal [MPC-11] - Isotype control (ab253068)

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Overview

  • Product name

    violetFluor™ 450 Mouse IgG2b, monoclonal [MPC-11] - Isotype control
    See all IgG2b isotype controls
  • Conjugation

    violetFluor™ 450. Ex: 405nm, Em: 450nm
  • Specificity

    ab253068 has an unknown binding specificity.

  • Tested applications

    Suitable for: Flow Cytmore details

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.16% Sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
  • Concentration information loading...
  • Purity

    Affinity purified
  • Purification notes

    Purified from tissue culture supernatant. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
  • Clonality

    Monoclonal
  • Clone number

    MPC-11
  • Isotype

    IgG2b
  • Research areas

    • Immunology
    • Immunoglobulins
    • Heavy Chain
    • IgG
  • Relevance

    IgG2 is divided into two subclasses; IgG2a and IgG2b. It is a glycoprotein which consists oftwo identical heavy chains (50 kDa each) and two identical light chains (25 kDa each), to give a combined mass of approximately 150 kDa. The chains are held in place by covalent disulfide bonds. Each light chain contains two immunoglobulin (Ig domains, while the heavy chains contain four Ig domains each. In the middle of each heavy chain is a relative varying portion called the “hinge region” which is unique to each IgG. This region allows for molecular flexibility and sets IgG apart from its IgG counter-parts. Properties of IgG2b include neutralization of toxins and diffusion in the extracellular space.
  • Cellular localization

    Secreted
  • Alternative names

    • gamma2b
    • Ig gamma-2B chain C region
    • Igh-3
    • IGHG2B
    • Immunoglobulin G2b
    see all

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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