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Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKC

Verbascoside, PKC inhibitor (ab143730)

Key features and details

  • PKC inhibitor. NF-κB inhibitor.
  • CAS Number: 61276-17-3
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Verbascoside, PKC inhibitor
  • Description

    PKC inhibitor. NF-κB inhibitor.
  • Biological description

    PKC inhibitor. NF-κB inhibitor. Increases PARP-1 and p53. Induces cell cycle arrest and differentiation. Inhibits MMP (IC50 = 32 μM). Shows anti-inflammatory, antinociceptive and antioxidant effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    61276-17-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
  • Molecular weight

    624.59
  • Molecular formula

    C29H36O15
  • PubChem identifier

    5281800
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • PKC
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Other
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Protein Kinase C
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Metabolism
    • Types of disease
    • Obesity
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • PARP
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • p53
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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