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Immunology Innate Immunity Macrophage / Inflamm.

U-75302, Leukotriene B4 BLT1 receptor antagonist (ab141736)

Key features and details

  • Selective leukotriene B4 BLT1 receptor antagonist
  • CAS Number: 119477-85-9
  • Purity: > 99%
  • Soluble in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    U-75302, Leukotriene B4 BLT1 receptor antagonist
  • Description

    Selective leukotriene B4 BLT1 receptor antagonist
  • Biological description

    Selective leukotriene B4 BLT1 receptor antagonist (IC50 = 1.5 μM). Active in vitro and in vivo. Inhibits innate immune response and augments the leukocyte antiadesive effect of aspirin.
  • Purity

    > 99%
  • CAS Number

    119477-85-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5S)-6-[6-[(1E,3R,5Z)-3-Hydroxyundeca-1,5-dienyl]pyridin-2-yl]hexane-1,5-diol
  • Molecular weight

    361.50
  • Molecular formula

    C22H35NO3
  • PubChem identifier

    6449854
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC=CCC(C=CC1=NC(=CC=C1)CC(CCCCO)O)O
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Innate Immunity
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    • Leukotriene & Related
    • Biochemicals
    • Research Area
    • Heart disease
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