U-18666A, cholesterol transport inhibitor (ab269882)
Key features and details
- Inhibitor of cholesterol synthesis and cellular transport
- CAS Number: 3039-71-2
- Soluble in DMSO to 50 mM and in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
U-18666A, cholesterol transport inhibitor -
Description
Inhibitor of cholesterol synthesis and cellular transport -
Biological description
Inhibitor of cholesterol synthesis and cellular transport. Impairs intracellular transport of LDL-derived cholesterol in CHO cells. Blocks the ability of LDL-derived cholesterol to suppress HMG-CoA reductase and LDL receptor activity. Weak inhibitor of Hedgehog signaling. Modulates APP cleavage in cultured cells. Tool compound for studying Niemann-Pick disease.
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CAS Number
3039-71-2 -
Chemical structure
Properties
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Chemical name
(3β)-3-[2-(Diethylamino)ethoxy]-androst-5-en-17-one, hydrochloride -
Molecular weight
424.07 -
Molecular formula
C25H41NO2.HCl -
PubChem identifier
9954082 -
Storage instructions
Shipped at Room Temperature. Store at Room Temperature. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 50 mM and in water to 50 mM -
Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN(CC)CCO[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C.Cl -
Source
Synthetic
Images
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Chemical Structure - U-18666A, cholesterol transport inhibitor (ab269882)
Chemical structure of U-18666A, cholesterol transport inhibitor, 3039-71-2
