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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Tyrphostin 1 (Tyrphostin A1), Inactive tyrphostin (ab145235)

Key features and details

  • Inactive tyrphostin
  • CAS Number: 2826-26-8
  • Purity: > 99%
  • Soluble in ethanol to 100 mM (with warming) and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Tyrphostin 1 (Tyrphostin A1), Inactive tyrphostin
  • Description

    Inactive tyrphostin
  • Alternative names

    • Tyrphostin A1
  • Biological description

    Inactive tyrphostin. Negative control for tyrphostins such as AG 490 (ab120950). Inhibits CD40 signaling pathway. Reduces IL-12 production in macrophages. Blocks CD40L-induced translocation of NFκB to the nucleus. Shows antiallergic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    2826-26-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[(4-Methoxyphenyl)methylidene]propanedinitrile
  • Molecular weight

    184.20
  • Molecular formula

    C11H8N2O
  • PubChem identifier

    2063
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 100 mM (with warming) and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC=C(C=C1)C=C(C#N)C#N
  • Source

    Synthetic

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