TY-52156 (ab254244)
Key features and details
- Novel S1P3 receptor antagonist
- CAS Number: 934369-14-9
- Purity: > 98%
Soluble in DMSO to 75 mM and in Ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TY-52156 -
Description
Novel S1P3 receptor antagonist -
Alternative names
- N-(4-Chlorophenyl)-3,3-dimethyl-2-oxobutanimidic 2-(4- chlorophenyl) hydrazide
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Biological description
Novel S1P3 receptor antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase inintracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4. Suppresses FTY-720-induced S1P3 receptor-mediated bradycardia in vivo. Inhibits S1P-induced breast cancer stem cell expansion in vitro.
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Purity
> 98% -
General notes
Protect from air and light.
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CAS Number
934369-14-9 -
Chemical structure
Properties
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Chemical name
N-(4-Chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide
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Molecular weight
364.27 -
Molecular formula
C18H19Cl2N3O -
PubChem identifier
16046248 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store In the Dark. -
Solubility overview
Soluble in DMSO to 75 mM and in Ethanol to 75 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C)C(=O)C(=NC1=CC=C(C=C1)Cl)NNC2=CC=C(C=C2)Cl -
Source
Synthetic
