Tryprostatin A, MAP-dependent microtubule assembly inhibitor (ab143558)
Key features and details
- Selective MAP-dependent microtubule assembly inhibitor
- CAS Number: 171864-80-5
- Purity: > 92%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Tryprostatin A, MAP-dependent microtubule assembly inhibitor -
Description
Selective MAP-dependent microtubule assembly inhibitor -
Biological description
Selective MAP-dependent microtubule assembly inhibitor. Disrupts mitotic spindle. Induces cell cycle arrest at G2/M phase. Inhibits BCRP. Shows antimitotic effects. -
Purity
> 92% -
CAS Number
171864-80-5 -
Chemical structure
Properties
-
Chemical name
(3S,8aS)-3-[[6-methoxy-2-(3-methylbut-2-enyl)-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione -
Molecular weight
381.47 -
Molecular formula
C22H27N3O3 -
PubChem identifier
9929833 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC(=CCC1=C(C2=C(N1)C=C(C=C2)OC)CC3C(=O)N4CCCC4C(=O)N3)C -
Source
Synthetic
-
Research areas
