Tosedostat (CHR2797) (ab273387)
Key features and details
- Aminopeptidase inhibitor
- CAS Number: 238750-77-1
- Purity: >= 98%
Soluble in DMSO to 100 mM and ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tosedostat (CHR2797) -
Description
Aminopeptidase inhibitor -
Biological description
Aminopeptidase inhibitor (IC50 values are 100, 150, 220, > 1000, > 5000, > 10000 and > 30000 nM for LAP, PuSA, aminopeptidase N, aminopeptidase B, PILSAP, LTA4 hydrolase and MetAP2, respectively). Potently inhibits myeloma cells proliferation and induces tumor growth apoptosis. Effect in cell resistance to conventional chemotherapeutics.
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Purity
>= 98% -
General notes
Protect from air.
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CAS Number
238750-77-1 -
Chemical structure
Properties
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Chemical name
(αS)-cyclopentyl ester-α-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2- oxoethyl]-4-methyl-1-oxopentyl]amino]-benzeneacetic acid
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Molecular weight
406.47 -
Molecular formula
C21H30N2O6 -
PubChem identifier
15547703 -
Storage instructions
Shipped at 4°C. Store at -20°C. It is important to note that this is air sensitive and impurities can occur as a result of air oxidation. Store In the Dark. -
Solubility overview
Soluble in DMSO to 100 mM and ethanol to 50 mM
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C[C@H]([C@@H](C(=O)NO)O)C(=O)N[C@@H](C1=CC=CC=C1)C(=O)OC2CCCC2 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Tosedostat (CHR2797) (ab273387)
Chemical structure of Tosedostat (CHR2797), 238750-77-1