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Biochemicals

Tirapazamine, cytotoxic agent (ab141976)

Key features and details

  • Potent cytotoxic agent
  • CAS Number: 27314-97-2
  • Purity: > 98%
  • Soluble in DMSO to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Tirapazamine, cytotoxic agent
  • Description

    Potent cytotoxic agent
  • Biological description

    Potent cytotoxic agent. Induces apoptosis due to breaks in single and double stranded DNA and chromosomes. Sensitizes cells to ionizing radiation and other cytotoxic agents.
  • Purity

    > 98%
  • CAS Number

    27314-97-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine
  • Molecular weight

    178.15
  • Molecular formula

    C7H6N4O2
  • PubChem identifier

    33776
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C2C(=C1)N(C(=N)N=[N+]2[O-])O
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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