Tiliroside, CYP inhibitor (ab141455)
Key features and details
- Reversible, competitive CYP inhibitor. Anti-inflammatory and antioxidant agent.
- CAS Number: 20316-62-5
- Purity: > 98%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tiliroside, CYP inhibitor -
Description
Reversible, competitive CYP inhibitor. Anti-inflammatory and antioxidant agent. -
Biological description
Anti-inflammatory and antioxidant agent. Reversible, competitive CYP inhibitor (IC50 values are 9, 10 and 12 μM for CYP3A4, CYP2C9 and CYP2C8 respectively). Inhibts NO, TNF-α and IL-12 production in activated macrophages. Antihypertensive and antiobesigenic effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
20316-62-5 -
Chemical structure
Properties
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Chemical name
[(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate -
Molecular weight
594.52 -
Molecular formula
C30H26O13 -
PubChem identifier
5320686 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1C=CC(=O)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)O)O)O)O -
Source
Synthetic
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Research areas
