Ticagrelor, P2Y12 receptor antagonist (ab230366)
Key features and details
- Reversible P2Y12 receptor antagonist
- CAS Number: 274693-27-5
- Purity: > 98%
Ticagrelor has a solubility of approximately 0.15 mg/ml in a 1:5 solution of DMF:PBS (pH 7.2). We do not recommend storing the aqueous solution for more than one day.
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Ticagrelor, P2Y12 receptor antagonist -
Description
Reversible P2Y12 receptor antagonist -
Alternative names
- AZD 6140
- Brilinta
- Brilique
-
Biological description
Reversible antagonist of the platelet purinergic P2Y12 receptor, the main receptor responsible for ADP-
induced platelet aggregation. Changes the conformation of the P2Y12 receptor, resulting in reversible, concentration dependent inhibition of the receptor. -
Purity
> 98% -
CAS Number
274693-27-5 -
Chemical structure
Properties
-
Chemical name
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
-
Molecular weight
522.57 -
Molecular formula
C23H28F2N6O4S -
PubChem identifier
9871419 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
Ticagrelor has a solubility of approximately 0.15 mg/ml in a 1:5 solution of DMF:PBS (pH 7.2). We do not recommend storing the aqueous solution for more than one day.
-
SMILES
FC(C(F)=C1)=CC=C1[C@@H]2C[C@H]2NC3=C4C(N([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)N=N4)=NC(SCCC)=N3 -
Source
Synthetic
-
Research areas
