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Ticagrelor, P2Y12 receptor antagonist (ab230366)

Key features and details

  • Reversible P2Y12  receptor antagonist
  • CAS Number: 274693-27-5
  • Purity: > 98%

  • Ticagrelor has a solubility of approximately 0.15 mg/ml in a 1:5 solution of DMF:PBS (pH 7.2). We do not recommend storing the aqueous solution for more than one day.

  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    Ticagrelor, P2Y12 receptor antagonist

  • Description

    Reversible P2Y12  receptor antagonist

  • Alternative names

    • AZD 6140
    • Brilinta
    • Brilique

  • Biological description

    Reversible antagonist of the platelet purinergic P2Y12 receptor, the main receptor responsible for ADP-induced platelet aggregation. Changes the conformation of the P2Y12 receptor, resulting in reversible, concentration dependent inhibition of the receptor. 

  • Purity

    > 98%

  • CAS Number

    274693-27-5

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

  • Molecular weight

    522.57

  • Molecular formula

    C23H28F2N6O4S

  • PubChem identifier

    9871419

  • Storage instructions

    Shipped at 4°C. Store at -20°C.

  • Solubility overview

    Ticagrelor has a solubility of approximately 0.15 mg/ml in a 1:5 solution of DMF:PBS (pH 7.2). We do not recommend storing the aqueous solution for more than one day.

  • SMILES

    FC(C(F)=C1)=CC=C1[C@@H]2C[C@H]2NC3=C4C(N([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)N=N4)=NC(SCCC)=N3

  • Source

    Synthetic

  • Research areas

Images

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