Teneligliptin, DPP-4 inhibitor (ab235551)
Key features and details
- Potent, long-lasting DPP-4 inhibitor
- CAS Number: 760937-92-6
- Purity: > 98%
Soluble in water to 159.01 mM, in DMSO to 159.01 mM and in ethanol to 27.03 mM.
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Teneligliptin, DPP-4 inhibitor -
Description
Potent, long-lasting DPP-4 inhibitor -
Alternative names
- Teneglucon
- Tenelia
- Tenepure
- Teneria
-
Biological description
Potent, long-lasting DPP-4 (dipeptidylpeptidase-4) inhibitor. Competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro (IC50 = ~ 1 nM). Attenuates lipogenesis in the liver by activating AMPK and downregulating the expression of genes involved in lipogenesis. Improves metabolic abnormalities in a mouse model of postmenopausal obesity.
-
Purity
> 98% -
CAS Number
760937-92-6 -
Chemical structure
Properties
-
Chemical name
((2S,4S)-4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone
-
Molecular weight
426.58 -
Molecular formula
C22H30N6OS -
PubChem identifier
11949652 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 159.01 mM, in DMSO to 159.01 mM and in ethanol to 27.03 mM.
-
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5 -
Source
Synthetic
-
Research areas
