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Cell Biology Proteolysis / Ubiquitin Proteasome / Ubiquitin Deubiquitination

TCID, ubiquitin C-terminal hydrolase-L3 inhibitor (ab144528)

Key features and details

  • Potent and selective ubiquitin C-terminal hydrolase-L3 inhibitor
  • CAS Number: 30675-13-9
  • Purity: > 95%
  • Soluble in DMSO to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    TCID, ubiquitin C-terminal hydrolase-L3 inhibitor
  • Description

    Potent and selective ubiquitin C-terminal hydrolase-L3 inhibitor
  • Biological description

    Potent and selective ubiquitin C-terminal hydrolase-L3 inhibitor (IC50 values are 0.6 and 75 μM for UCH-L3 and UCH-L1 respectively). Reduces GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
  • Purity

    > 95%
  • CAS Number

    30675-13-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4,5,6,7-Tetrachloroindan-1,3-dione
  • Molecular weight

    283.93
  • Molecular formula

    C9H2Cl4O2
  • PubChem identifier

    2729042
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteasome / Ubiquitin
    • Deubiquitination
    • Epigenetics and Nuclear Signaling
    • Ubiquitin & Ubiquitin Like Modifiers
    • Deubiquitination

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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