TBBz, protein kinase CK2 inhibitor (ab143860)
Key features and details
- Selective ATP-competitive inhibitor of protein kinase CK2.
- CAS Number: 577779-57-8
- DMSO, ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TBBz, protein kinase CK2 inhibitor -
Description
Selective ATP-competitive inhibitor of protein kinase CK2. -
Alternative names
- 4,5,6,7-tetrabromo-1H-benzimidazole
- 4,5,6,7-Tetrabromobenzimidazole
- Casein Kinase II Inhibitor XII
- CK2 Inhibitor
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Biological description
Selective, cell-permeable ATP-competitive inhibitor of protein kinase CK2 from such divergent sources as yeast, rat liver, Neurospora erassa and Candida tropicalis, with Ki values in the range of 0.5-1uM. It is virtually inactive against PKA, PKC, and a very weak inhibitor of protein kinase CK1.
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CAS Number
577779-57-8 -
Chemical structure
Properties
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Chemical name
4,5,6,7-Tetrabromobenzimidazole -
Molecular weight
433.72 -
Molecular formula
C7H2Br4N2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
DMSO, ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
