Suc-Leu-Leu-Val-Tyr-AMC, Fluorogenic substrate of calpains and 20S proteasome (ab142120)
Key features and details
- Fluorogenic substrate of calpains and 20S proteasome
- CAS Number: 94367-21-2
- Purity: > 97%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Suc-Leu-Leu-Val-Tyr-AMC, Fluorogenic substrate of calpains and 20S proteasome -
Description
Fluorogenic substrate of calpains and 20S proteasome -
Biological description
Fluorogenic substrate of calpains and 20S proteasome. Calpain I and II hydrolyses Suc-Leu-Leu-Val-Tyr-AMC with Km values of 203 and 466 µM, respectively. Used to study the activity of calpains and proteosomal degradation.
-
Purity
> 97% -
CAS Number
94367-21-2 -
Chemical structure
Properties
-
Molecular weight
763.89 -
Molecular formula
C40H53N5O10 -
Sequence
LLVY (Modifications: N-terminal succinyl; C-terminal AMC) -
PubChem identifier
10234210 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CCC(=O)O -
Source
Synthetic
-
Research areas
