Staurosporine (DMSO solution), protein kinase inhibitor (ab146588)
Key features and details
- Protein kinase inhibitor
- CAS Number: 62996-74-1
- Purity: > 98%
- Supplied in DMSO (1mM)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Staurosporine (DMSO solution), protein kinase inhibitor -
Description
Protein kinase inhibitor -
Biological description
Potent, cell-permeable, broad spectrum inhibitor of protein kinases. Kinases inhibited include: protein kinase C (IC50 = 3 nM), cAMP-dependent protein kinase (IC50 = 8 nM) and p60v-src (IC50 = 6 nM).
Also available as a solid (ab120056). -
Purity
> 98% -
CAS Number
62996-74-1 -
Chemical structure
Properties
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Chemical name
[9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3,2,1-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one -
Molecular weight
466.54 -
Molecular formula
C28H26N4O3 -
PubChem identifier
44259 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (1mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C6NCc5c2c4n(c1ccccc12)[C@@]3(C)O[C@H](C[C@@H](NC)[C@H]3OC)n7c4c(c56)c8ccccc78 -
Source
Synthetic
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Research areas
