SM 7368, NF-kappaB inhibitor (ab146120)
Key features and details
- Selective NF-κB inhibitor
- CAS Number: 380623-76-7
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
SM 7368, NF-kappaB inhibitor -
Description
Selective NF-κB inhibitor -
Biological description
Selective NF-κB inhibitor. Inhibits TNF-α induced MMP-9 expression. Decreases MMP-9 expression in AMPKα knockout cells. Putative antimetastatic agent.
-
Purity
> 99% -
CAS Number
380623-76-7 -
Chemical structure
Properties
-
Chemical name
3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)benzamide -
Molecular weight
328.69 -
Molecular formula
C10H5ClN4O5S -
PubChem identifier
11537217 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1=CC(=C(C=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-])Cl)[N+](=O)[O-] -
Source
Synthetic
-
Research areas