SL 327, MEK inhibitor (ab120082)
Key features and details
- MEK inhibitor
- CAS Number: 305350-87-2
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SL 327, MEK inhibitor -
Description
MEK inhibitor -
Biological description
Centrally active, brain penetrant selective MEK1 and MEK2 inhibitor (IC50 values in in vitro assays are 0.18 and 0.22 μM, respectively).
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Purity
> 99% -
CAS Number
305350-87-2 -
Chemical structure
Properties
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Chemical name
α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile -
Molecular weight
335.34 -
Molecular formula
C16H12F3N3S -
PubChem identifier
9549284 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM (with heating) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
N/C(Sc1ccc(N)cc1)=C(/[N+]#[C-])c2ccccc2C(F)(F)F -
Source
Synthetic
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Research areas
