SKI-II, Sphingosine kinase (SK1/2) inhibitor (ab141594)
Key features and details
- Sphingosine kinase (SK1/2) inhibitor
- CAS Number: 312636-16-1
- Purity: > 98%
- Soluble in DMSO to 75 mM and in ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SKI-II, Sphingosine kinase (SK1/2) inhibitor -
Description
Sphingosine kinase (SK1/2) inhibitor -
Biological description
Sphingosine kinase (SK1/2) inhibitor (IC50 values are 35 and 20 μM for SK1 and SK2 respectively). Inhibits tumor growth in vivo. Orally active. -
Purity
> 98% -
CAS Number
312636-16-1 -
Chemical structure
Properties
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Chemical name
4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol -
Molecular weight
302.80 -
Molecular formula
C15H11ClN2OS -
PubChem identifier
753704 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM and in ethanol to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl -
Source
Synthetic
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Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
