SKI-I, Sphingosine Kinase Inhibitor (ab142209)
Key features and details
- Specific non-lipid sphingosine kinase (SK) inhibitor. Cell-permeable.
- CAS Number: 306301-68-8
- Purity: > 90%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SKI-I, Sphingosine Kinase Inhibitor -
Description
Specific non-lipid sphingosine kinase (SK) inhibitor. Cell-permeable. -
Biological description
Specific non-lipid sphingosine kinase (SK) inhibitor. Inhibits SK1 and SK2. Inhibits sphingosine 1-phosphate (S1P) production and pro-apoptotic. Induces autophagy. Cell permeable and active in vivo and in vitro.
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Purity
> 90% -
CAS Number
306301-68-8 -
Chemical structure
Properties
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Chemical name
5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylic acid 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide -
Molecular weight
406.44 -
Molecular formula
C25H18N4O2 -
PubChem identifier
137269090 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C(NNC1C(=O)N/N=C/C2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4 -
Source
Synthetic
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Research areas
