SIRT inhibitor 1/2 VII (ab144550)
Key features and details
- Sirtuin and NAD+-dependent class III HDAC inhibitor
- CAS Number: 143034-06-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SIRT inhibitor 1/2 VII -
Description
Sirtuin and NAD+-dependent class III HDAC inhibitor -
Biological description
Sirtuin and NAD+-dependent class III HDAC inhibitor (IC50 values are 13.2 and 9.1 µM for SIRT1 and SIRT2, respectively). Thiobarbiturate compound.
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Purity
> 98% -
CAS Number
143034-06-4 -
Chemical structure
Properties
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Chemical name
Dihydro-5-(1-naphthalenylmethylene)-2-thioxo-4,6(1H,5H)-pyrimidinedione -
Molecular weight
282.32 -
Molecular formula
C15H10N2O2S -
PubChem identifier
694858 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C2C(=C1)C=CC=C2C=C3C(=O)NC(=S)NC3=O -
Source
Synthetic
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Research areas