SHU9119, Melanocortin 3 and 4 (MC3 and MC4) receptor antagonist (ab141164)
Key features and details
- Potent melanocortin 3 and 4 (MC3 and MC4) receptor antagonist
- CAS Number: 168482-23-3
- Purity: > 95%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SHU9119, Melanocortin 3 and 4 (MC3 and MC4) receptor antagonist -
Description
Potent melanocortin 3 and 4 (MC3 and MC4) receptor antagonist -
Biological description
Potent melanocortin 3 and 4 (MC3 and MC4) receptor antagonist (IC50 values are 0.23 and 0.06 nM, respectively). Also shows MC5 partial agonist activity (EC50 = 0.12 nM). Dose-dependently increases food intake following central administration.
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Purity
> 95% -
CAS Number
168482-23-3 -
Chemical structure
Properties
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Molecular weight
1074.25 -
Molecular formula
C54H71N15O9 -
Sequence
XDHXRWK (Modifications: N-terminal acetyl; C-terminal amide; X-1 = D-2-Nal; X-4 = Nle; Cyclised: 2-7) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
