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Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKB / AKT

SH-6, Akt inhibitor (ab141443)

Key features and details

  • Phosphatidylinositol analog; selective Akt inhibitor
  • CAS Number: 701976-55-8
  • Purity: > 98%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SH-6, Akt inhibitor
  • Description

    Phosphatidylinositol analog; selective Akt inhibitor
  • Biological description

    Phosphatidylinositol analog. Selective Akt inhibitor, prevents Akt translocation to the membrane. Has no effect on other downstream kinases. Induces apoptosis.
  • Purity

    > 98%
  • CAS Number

    701976-55-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(2R)-2-Methoxy-3-octadecoxypropyl] (2,3,4-trihydroxycyclohexyl) hydrogen phosphate
  • Molecular weight

    568.72
  • Molecular formula

    C28H57O9P
  • PubChem identifier

    16760283
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OC1CCC(C(C1O)O)O)OC
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • PKB / AKT
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Heart disease
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Diabetes
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Heart disease
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Hypertension
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Obesity
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Stroke
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Akt
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • PI3K/Akt signaling
    • Akt
    • Inhibitors
    • Biochemicals
    • Research Area
    • Cancer
    • Signal transduction
    • PI3K/Akt signaling
    • Akt
    • Inhibitors

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