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Neuroscience Neurotransmitter Transporters GABA

Securinine, GABA receptor antagonist (ab142462)

Key features and details

  • Selective GABA receptor antagonist
  • CAS Number: 5610-40-2
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Securinine, GABA receptor antagonist
  • Description

    Selective GABA receptor antagonist
  • Biological description

    Selective GABA receptor antagonist. Active in vivo. Induces apoptosis in human leukemia HL-60 cells.
  • Purity

    > 98%
  • CAS Number

    5610-40-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Securinan-11-one
  • Molecular weight

    217.26
  • Molecular formula

    C13H15NO2
  • PubChem identifier

    442872
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CCN2C(C1)C34CC2C=CC3=CC(=O)O4
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Amino Acids
    • GABA
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • GABA
    • Non-selective
    • Antagonists

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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