SB 225002, non-peptide CXCR2 antagonist (ab120895)
Key features and details
- A selective non-peptide CXCR2 antagonist
- CAS Number: 182498-32-4
- Purity: > 95%
- Soluble in DMSO to 75 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB 225002, non-peptide CXCR2 antagonist -
Description
A selective non-peptide CXCR2 antagonist -
Biological description
A selective non-peptide CXCR2 antagonist. Inhibits IL-8 binding to CXCR2 (IC50 = 22 nM). -
Purity
> 95% -
CAS Number
182498-32-4 -
Chemical structure
Properties
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Chemical name
N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea -
Molecular weight
352.14 -
Molecular formula
C13H10BrN3O4 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC1=CC([N+]([O-])=O)=CC=C1NC(NC2=C(Br)C=CC=C2)=O -
Source
Synthetic
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Research areas