S-(4-Nitrobenzyl)-6-thioinosine, ENT1 inhibitor (ab145027)
Key features and details
- Equilibrative nucleoside transporter (ENT1) inhibitor.
- CAS Number: 38048-32-7
- DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
S-(4-Nitrobenzyl)-6-thioinosine, ENT1 inhibitor -
Description
Equilibrative nucleoside transporter (ENT1) inhibitor. -
Alternative names
- 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine; 6
- NBMPR
- NBTI
- S-(p-Nitrobenzyl)-6-mercapto
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Biological description
Nucleoside analog that competitively inhibits equilibrative nucleoside transporter 1 (ENT1) (IC50s = 4.6 and 3.6 nM for rat and human, respectively).
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CAS Number
38048-32-7 -
Chemical structure
Properties
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Chemical name
6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine -
Molecular weight
419.41 -
Molecular formula
C17H17N5O6S -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic