Rubratoxin A, PP2A inhibitor (ab144347)
Key features and details
- Potent, selective, competitive PP2A inhibitor
- CAS Number: 22467-31-8
- Purity: > 95%
- Soluble in ethanol in and DMSO
- Form / State: Solid
- Source: Penicillium sp.
Overview
-
Product name
Rubratoxin A, PP2A inhibitor -
Description
Potent, selective, competitive PP2A inhibitor -
Biological description
Potent, selective, competitive PP2A inhibitor (Ki = 28.7 nM). Rubratoxin B analog. Induces caspase-dependent decrease in cell viability. Shows antitumor effects in vivo. -
Purity
> 95% -
CAS Number
22467-31-8 -
Chemical structure
Properties
-
Chemical name
9-((3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl)-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona(c)furan-6,7-dicarboxylic anhydride -
Molecular weight
520.53 -
Molecular formula
C26H32O11 -
PubChem identifier
56840856 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol in and DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CCCCCC[C@@H](C1[C@@H](C2=C(CC(CC3=C1C(=O)OC3O)[C@@H](C4CC=CC(=O)O4)O)C(=O)OC2=O)O)O -
Source
Penicillium sp.
-
Research areas