5-Methoxysterigmatocystin, Antiproliferative agent (ab144300)
Key features and details
- Mycotoxin. Sterigmatocystin derivative. Antiproliferative agent.
- CAS Number: 22897-08-1
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Aspergillus sp.
Overview
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Product name
5-Methoxysterigmatocystin, Antiproliferative agent -
Description
Mycotoxin. Sterigmatocystin derivative. Antiproliferative agent. -
Biological description
Mycotoxin. Sterigmatocystin (ab143698) derivative. Antiproliferative agent (IC50 = 181 μM, adenocarcinoma lung cells). Shows cytotoxic effects (IC50 values are 3.86 and 5.32 μM for A-549 and HL-60 cell lines respectively). Shows antitumor effects. -
Purity
> 98% -
CAS Number
22897-08-1 -
Chemical structure
Properties
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Chemical name
(3aR-cis)-3a,12c-Dihydro-8-hydroxy-6,11-dimethoxy-7H-furo[3',5]furo[2,3-c]xanthen-7-one -
Molecular weight
354.31 -
Molecular formula
C19H14O7 -
PubChem identifier
5351257 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C2C(=C(C=C1)O)C(=O)C3=C(C=C4C(=C3O2)[C@@H]5C=CO[C@@H]5O4)O -
Source
Aspergillus sp.
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Research areas